وصفه و خلطة أعشاب

If a substance is deemed  safe  for use in food, allowable levels are determined . Experts from the  FDA  and the FAO/WHO evaluate all the data from the tests and from human safe food levels in food exposure. NOEL is used as the safe level(vsl) for a compound. The ADI is the amount of substance certainly , on the basis of known facts, that no harm will result . ADIs may be expressed for a group of related compounds. The VSL has been suggested for carcinogens for which a dose-response relationship has been established from linear extrapolation. To set the ADI, NOEL is divided by at least 100 to ensure a margin of safety. Such a 100-fold margin of safety is necessary to allow for the fact that the number of animals tested is small compared to the size of the human population that may be exposed. Further the most sensitive individual is assumed to be 10 times more sensitive than the most susceptible animal. For carcinogens , a safet...