- carcinogenisis
The 3 stages of Carcinogenesis
1. Initiation(the first stage of carcinogenisis)
During this stage, some event or chemical begins the transformation of a single cell into a multicellular, malignant tumor.
Information of a single cell into a multicellular, malignant tumor. In most cases, this is believed to involve a permanent , irreversible change, probably consisting of a genetic mutation.
Once initiation has begun , the cell has the potential to develop into a tumor , provided that the other essential steps of Carcinogenesis take place. If these other steps do not take place, the initiated cell may remain dormant indefinitely with no apparent effect on the organism.
2. Promotion(the second stage of carcinogenisis)
During this carcinogenisis stage , the initiated cell clones itself and expands within a given tissue, As the number of these target cells increases, there are many sites where changes can produce fully malignant cells.
3. Progression(the third stage of carcinogenisis)
As the target cells multiply further, other changes such as chromosomal rearrangements, point mutations, and additions or deletions to genetic material, as well as non-genetic changes, may take place until the tumor consists of a heterogeneous population of cells.
Eventually, one or more of these cells emerges with all the characteristics of a neoplastic cell. That was my post to you to know about the stages of Carcinogenesis.Hope that you've enjoyed reading it .
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